"Heart-Shaped Box" is a song by the American rock band Nirvana, written by vocalist and guitarist, Kurt Cobain. It appears as the third track on the band's third and final studio album, In Utero, released by DGC Records in September 1993. It was one of two songs on In Utero remixed by Scott Litt prior to the album's release, due to the band's dissatisfaction with the original mixing by producer Steve Albini. The Litt remix also featured additional vocal harmonies and guitar by Cobain, which were the only elements on the album's 12 main tracks not recorded during the original sessions with Albini in February 1993.

"Heart-Shaped Box" was released as the In Utero's first single on August 30, 1993. Although the single was not released in the United States, to avoid competing with album sales, the song generated considerable American radio airplay, reaching number one on the Billboard Modern Rock Tracks chart. The physical single reached the top 10 in several countries, including Portugal, the United Kingdom, Ireland, Finland, and New Zealand.

"Heart-Shaped Box" was the final Nirvana song to receive a music video before the suicide of Cobain in April 1994. The video, directed by Anton Corbijn, won two awards, including Best Alternative Video, at the 1994 MTV Video Music Awards.

"Heart-Shaped Box" was the final song performed at Nirvana's last concert, on March 1, 1994, in Munich, Germany.